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PIK3R1(Tyr556) Antibody

PIK3R1(Tyr556) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePIK3R1(Tyr556) Primary Polyclonal Antibody
Also known asPIK3R1(Tyr556) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPIK3R1 Tyr556
SpecificityThis is a highly specific antibody against PIK3R1 Tyr556
Modification(s)Phosphorylation
Modification site(s)Tyr556
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr556 [AE(p-Y)RE]
Gene ID number5295
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 4, 5-triphosphate in response to receptor activation in many signal transduction pathways, Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e, p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane, p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues, p85 alpha), The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, g
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GRB1, PI3 kinase p85 alpha subunit, PI3 kinase p85 subunit alpha, PI3K , PIK3R1, Phosphatidylinositol 3 kinase associated p85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase regulatory alpha subunit, Phosphoinositide 3 kinase regulatory subunit polypeptide 1 p85 alpha, PtdIns 3 kinase p85 alpha, p50 alpha, p55 alpha, p85, p85 alpha, PIK3R1phospho Y556
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPIK3R1(Tyr556)
Short namePIK3R1(Tyr556) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePIK3R1(Tyr556) (Antibody to)
Alternative techniqueantibodies
Identity 8979
Gene PIK3R1
Long gene name phosphoinositide-3-kinase regulatory subunit 1
Synonyms gene name phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Synonyms GRB1 p85-ALPHA p85
Synonyms name phosphoinositide-3-kinase regulatory subunit alpha
Locus 5q13, 1
Discovery year 1992-12-08
GenBank acession M61906
Entrez gene record 5295
Pubmed identfication 1314371 18387942
RefSeq identity NM_181504
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000131251
Locus Specific Databases SH2base: Database for pathogenic SH2 domain mutations LRG_453

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