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Pin1 Antibody, ALEXA FLUOR 647

Pin1 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, Pin1 Polyclonal Antibody
Also known asAnti-Pin1 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPin1
SpecificityThis is a highly specific antibody against Pin1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pin1
Gene ID Number5300
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding, Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau, Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration, Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain, Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease, Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds, Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation, Pin1 is a Peptidyl-prolyl isomerases (PPIase)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms dod
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Pin1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetPin1
Short namePin1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, NIMA-interacting 1 (Antibody to), peptidylprolyl cis/trans isomerase
Alternative techniqueantibodies
Identity 8988
Gene PIN1
Long gene name NIMA-interacting 1 , peptidylprolyl cis/trans isomerase
Synonyms gene name protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
Locus 19p13
Discovery year 1996-12-16
Entrez gene record 5300
Pubmed identfication 8606777
Classification Parvulins
Havana BLAST/BLAT OTTHUMG00000180388
Locus Specific Databases LRG_847

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