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Pin1 (Ser16) Antibody, Biotin Conjugated

Pin1 (Ser16) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Pin1 (Ser16) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPin1 Ser16
Specificity This phosphorylation site is homologous across the listed species, This is a highly specific antibody against Pin1 Ser16
ModificationPhosphorylation
Modification siteSer16
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1-50/163
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16
Gene ID number5300
Swiss ProtQ13526
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner, Can transactivate multiple oncogenes and induce centrosome amplification, Catalyzes pSer/Thr-Pro cis/trans isomerizations, Displays a preference for an acidic residue N-terminal to the isomerized proline bond, Down-regulates kinase activity of BTK, Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation, chromosome instability and cell transformation, Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PIN1, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, Rotamase Pin1, UBL5, DOD
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPin1 (Ser16) Conjugated
Short name Conjugated, Pin1 (Ser16) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name NIMA-interacting 1 (Ser16) (Antibody to), biotinilated coupled, peptidylprolyl cis/trans isomerase
Alternative techniqueantibodies

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