Name : PIRT Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1797458514
| Long name | PIRT Primary Polyclonal Antibody |
| Also known as | PIRT PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PIRT |
| Specificity | This is a highly specific antibody against PIRT |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PIRT |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Although PIRT is expressed in peripheral nervous system, Correspondingly, Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain, PIRT is a required component of the VR1 complex, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, The gene that encodes PIRT maps to human chromosome 17p13, a sensor of both noxious heat and capsaicin, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord, which positively regulates VR1, while VR1 remains unaltered, with highest levels in dorsal root ganglion and trigeminal neurons, 1, PIRT is a 137 amino acid multi-pass membrane protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | PIRT_HUMAN, Phosphoinositide interacting regulator of transient receptor potential channels , Phosphoinositide-interacting protein, Pirt, hCG_1776018 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PIRT |
| Short name | PIRT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PIRT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 37239 |
| Gene | PIRT |
| Long gene name | phosphoinositide interacting regulator of transient receptor potential channels |
| Synonyms gene name | phosphoinositide-interacting regulator of transient receptor potential channels |
| Synonyms name | phosphoinositide-interacting regulator of TRPV1 |
| Locus | 17p12 |
| Discovery year | 2010-06-04 |
| GenBank acession | AK021549 |
| Entrez gene record | 644139 |
| Pubmed identfication | 18455988 |
| RefSeq identity | NM_001101387 |
| Havana BLAST/BLAT | OTTHUMG00000178234 |