Name : PIRT Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9658815138
| Long name | ALEXA FLUOR 647 Conjugated, PIRT Polyclonal Antibody |
| Also known as | Anti-PIRT PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PIRT |
| Specificity | This is a highly specific antibody against PIRT |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PIRT |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Although PIRT is expressed in peripheral nervous system, Correspondingly, Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain, PIRT is a required component of the VR1 complex, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, The gene that encodes PIRT maps to human chromosome 17p13, a sensor of both noxious heat and capsaicin, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord, which positively regulates VR1, while VR1 remains unaltered, with highest levels in dorsal root ganglion and trigeminal neurons, 1, PIRT is a 137 amino acid multi-pass membrane protein |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PIRT Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | PIRT |
| Short name | PIRT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, PIRT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 37239 |
| Gene | PIRT |
| Long gene name | phosphoinositide interacting regulator of transient receptor potential channels |
| Synonyms gene name | phosphoinositide-interacting regulator of transient receptor potential channels |
| Synonyms name | phosphoinositide-interacting regulator of TRPV1 |
| Locus | 17p12 |
| Discovery year | 2010-06-04 |
| GenBank acession | AK021549 |
| Entrez gene record | 644139 |
| Pubmed identfication | 18455988 |
| RefSeq identity | NM_001101387 |
| Havana BLAST/BLAT | OTTHUMG00000178234 |