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PIRT Antibody, Biotin Conjugated

PIRT Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, PIRT Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPIRT
SpecificityThis is a highly specific antibody against PIRT
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PIRT
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although PIRT is expressed in peripheral nervous system, Correspondingly, Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain, PIRT is a required component of the VR1 complex, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, The gene that encodes PIRT maps to human chromosome 17p13, a sensor of both noxious heat and capsaicin, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord, which positively regulates VR1, while VR1 remains unaltered, with highest levels in dorsal root ganglion and trigeminal neurons, 1, PIRT is a 137 amino acid multi-pass membrane protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPIRT Conjugated
Short name Conjugated, PIRT Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PIRT (Antibody to)
Alternative techniqueantibodies
Identity 37239
Gene PIRT
Long gene name phosphoinositide interacting regulator of transient receptor potential channels
Synonyms gene name phosphoinositide-interacting regulator of transient receptor potential channels
Synonyms name phosphoinositide-interacting regulator of TRPV1
Locus 17p12
Discovery year 2010-06-04
GenBank acession AK021549
Entrez gene record 644139
Pubmed identfication 18455988
RefSeq identity NM_001101387
Havana BLAST/BLAT OTTHUMG00000178234

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