Name : PIRT Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5959100040
| Long name | Biotin Conjugated, PIRT Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PIRT |
| Specificity | This is a highly specific antibody against PIRT |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PIRT |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Although PIRT is expressed in peripheral nervous system, Correspondingly, Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain, PIRT is a required component of the VR1 complex, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, The gene that encodes PIRT maps to human chromosome 17p13, a sensor of both noxious heat and capsaicin, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord, which positively regulates VR1, while VR1 remains unaltered, with highest levels in dorsal root ganglion and trigeminal neurons, 1, PIRT is a 137 amino acid multi-pass membrane protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PIRT Conjugated |
| Short name | Conjugated, PIRT Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, PIRT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 37239 |
| Gene | PIRT |
| Long gene name | phosphoinositide interacting regulator of transient receptor potential channels |
| Synonyms gene name | phosphoinositide-interacting regulator of transient receptor potential channels |
| Synonyms name | phosphoinositide-interacting regulator of TRPV1 |
| Locus | 17p12 |
| Discovery year | 2010-06-04 |
| GenBank acession | AK021549 |
| Entrez gene record | 644139 |
| Pubmed identfication | 18455988 |
| RefSeq identity | NM_001101387 |
| Havana BLAST/BLAT | OTTHUMG00000178234 |