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PIST/GOPC Antibody

PIST/GOPC Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePIST/GOPC Primary Polyclonal Antibody
Also known asPIST/GOPC PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPIST/GOPC
SpecificityThis is a highly specific antibody against PIST/GOPC
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PIST
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, CAL or FIG, Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy, Three isoforms of PIST exist due to alternative splicing events, a common and aggressive form of brain tumor, also known as GOPC (golgi associated PDZ and coiled-coil motif containing), as well as to the membrane of the golgi apparatus and to the cell junction, is a 462 amino acid protein that localizes to the cytoplasm, suggesting a role for mutated PIST in carcinogenesis, PIST (PDZ protein interacting specifically with TC10)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CFTR associated ligand, CFTR-associated ligand, FIG, Fused in glioblastoma, GOPC, GOPC1, GOPC_HUMAN, Golgi associated PDZ and coiled coil mot containing, Golgi associated PDZ and coiled coil mot containing protein, Golgi-associated PDZ and coiled-coil mot-containing protein, OTTHUMP00000040403, PDZ protein interacting specically with TC 10, PDZ protein interacting specically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, PIST, Protein interacting specically with Tc 10, Protein interacting specically with Tc10, dJ94G16, dJ94G16, 2, 2 PIST, CAL
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPIST/GOPC
Short namePIST/GOPC Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePIST/GOPC (Antibody to)
Alternative techniqueantibodies
Identity 17643
Gene GOPC
Long gene name golgi associated PDZ and coiled-coil motif containing
Synonyms dJ94G16, 2 PIST FIG GOPC1 CAL
Locus 6q22, 1
Discovery year 2003-08-29
GenBank acession AF287894
Entrez gene record 57120
Pubmed identfication 11162552 11520064
RefSeq identity NM_020399
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000015457

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