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PIST/GOPC Antibody, FITC Conjugated

PIST/GOPC Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PIST/GOPC Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPIST/GOPC
SpecificityThis is a highly specific antibody against PIST/GOPC
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PIST
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, CAL or FIG, Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy, Three isoforms of PIST exist due to alternative splicing events, a common and aggressive form of brain tumor, also known as GOPC (golgi associated PDZ and coiled-coil motif containing), as well as to the membrane of the golgi apparatus and to the cell junction, is a 462 amino acid protein that localizes to the cytoplasm, suggesting a role for mutated PIST in carcinogenesis, PIST (PDZ protein interacting specifically with TC10)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms dJ94G16, 2 PIST FIG GOPC1 CAL
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPIST/GOPC Conjugated
Short name FITC Conjugated, PIST/GOPC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PIST/GOPC (Antibody to)
Alternative techniqueantibodies
Identity 17643
Gene GOPC
Long gene name golgi associated PDZ and coiled-coil motif containing
Locus 6q22, 1
Discovery year 2003-08-29
GenBank acession AF287894
Entrez gene record 57120
Pubmed identfication 11162552 11520064
RefSeq identity NM_020399
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000015457

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