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PKC alpha/beta II (Thr638/641) Antibody

PKC alpha/beta II (Thr638/641) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePKC alpha/beta II (Thr638/641) Antibody
Also known asPKC alpha/beta II (Thr638/641) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPKC alpha/beta II Thr638/641
SpecificityThis is a highly specific antibody against PKC alpha/beta II Thr638/641
Modification(s)Phosphorylation
Modification site(s)Thr638/641
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range606-641/672
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human PKC alpha/beta II around the phosphorylation site of Thr638/641
Gene ID number5578
Swiss ProtP17252
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Dog, Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1), This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation, and solute transport, cell cell adhesion, cell extracellular matrix adhesion, cell survival and transcriptional regulation, development, diacylglycerol, differentiation, migration, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PKC-A, PKC-alpha, PKCA, PRKACA, PRKCA, Protein kinase C alpha type, AAG6
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPKC alpha/beta II (Thr638/641)
Short namePKC alpha/beta II (Thr638/641) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePKC a/b II (Thr638/641) (Antibody to)
Alternative techniqueantibodies
Identity 30500
Gene PRRT2
Long gene name proline rich transmembrane protein 2
Synonyms gene ICCA DYT10
Synonyms gene name infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2
Synonyms FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1
Synonyms name interferon induced transmembrane protein domain containing 1
Locus 16p11, 2
Discovery year 2005-11-25
GenBank acession BC011405
Entrez gene record 112476
Pubmed identfication 22101681 22243967
RefSeq identity NM_145239
Classification Proline rich transmembrane proteins
Havana BLAST/BLAT OTTHUMG00000177142

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