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PKC alpha/beta II (Thr638/641) Antibody, FITC Conjugated

PKC alpha/beta II (Thr638/641) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PKC alpha/beta II (Thr638/641) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPKC alpha/beta II Thr638/641
SpecificityThis is a highly specific antibody against PKC alpha/beta II Thr638/641
ModificationPhosphorylation
Modification siteThr638/641
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range606-641/672
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human PKC alpha/beta II around the phosphorylation site of Thr638/641
Gene ID number5578
Swiss ProtP17252
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Dog, Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1), This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation, and solute transport, cell cell adhesion, cell extracellular matrix adhesion, cell survival and transcriptional regulation, development, diacylglycerol, differentiation, migration, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPKC alpha/beta II (Thr638/641) Conjugated
Short name FITC Conjugated, PKC alpha/beta II (Thr638/641) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PKC a/b II (Thr638/641) (Antibody to)
Alternative techniqueantibodies
Identity 30500
Gene PRRT2
Long gene name proline rich transmembrane protein 2
Synonyms gene ICCA DYT10
Synonyms gene name infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2
Synonyms name interferon induced transmembrane protein domain containing 1
Locus 16p11, 2
Discovery year 2005-11-25
GenBank acession BC011405
Entrez gene record 112476
Pubmed identfication 22101681 22243967
RefSeq identity NM_145239
Classification Proline rich transmembrane proteins
Havana BLAST/BLAT OTTHUMG00000177142

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