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PLCG2(Tyr1217) Antibody, Biotin Conjugated

PLCG2(Tyr1217) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PLCG2(Tyr1217) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPLCG2Tyr1217
SpecificityThis is a highly specific antibody against PLCG2Tyr1217
ModificationPhosphorylation
Modification siteTyr1217
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217
Gene ID number5336
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A number of these enzymes have specificity for phosphoinositides, C beta is regulated by heterotrimeric G protein coupled receptors, Of the phosphoinositide specific phospholipase C enzymes, SH2 and SH3, The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases, Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPLCG2(Tyr1217) Conjugated
Short name Conjugated, PLCG2(Tyr1217) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, gamma 2 (phosphatidylinositol-specific)(Tyr1217) (Antibody to), phospholipase C
Alternative techniqueantibodies
Alternative to gene target APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, gamma 2 (phosphatidylinositol-specific), phosphoric diester hydrolase activity, this GO :0002316 and follicular B cell differentiation and biological process this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004629 and phospholipase C activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008081 and phosphoric diester hydrolase activity and molecular function this GO :0009395 and phospholipid catabolic process and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0032237 and activation of store-operated calcium channel activity and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032959 and inositol trisphosphate biosynthetic process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043069 and negative regulation of programmed cell death and biological process this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004435: phosphatidylinositol phospholipase C activity, this GO :0004435: phosphatidylinositol phospholipase C activity and also this GO :0004629: phospholipase C activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008081: phosphoric diester hydrolase activity, this GO :0004629: phospholipase C activity, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008081: phosphoric diester hydrolase activity, phospholipase C
Identity 9066
Gene PLCG2
Long gene name phospholipase C gamma 2
Synonyms gene name gamma 2 (phosphatidylinositol-specific) , phospholipase C
Locus 16q24, 1
Discovery year 1994-05-16
Entrez gene record 5336
Pubmed identfication 7835906
Classification Phospholipases SH2 domain containing C2 domain containing phospholipases
Havana BLAST/BLAT OTTHUMG00000176532
Locus Specific Databases LRG_376

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