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PLEKHM1 Antibody, FITC Conjugated

PLEKHM1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PLEKHM1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPLEKHM1
SpecificityThis is a highly specific antibody against PLEKHM1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PLEKHM1
Gene ID number9842
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts, May have a role in sialyl-lex-mediated transduction of apoptotic signals, No expression in heart, Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, Predominantly expressed in the breast carcinoma cell line MCF-7, The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, Weakly expressed in brain, also known as autosomal recessive osteopetrosis intermediate form, and a benign autosomal dominant form occurring in adolescence or adulthood, and testis, colon, colon carcinoma and peripheral blood lymphocytes (PBL), due to defective resorption of immature bone, infancy, kidney, liver, lung, or childhood, ovary, pancreas and small intestine, prostate, skeletal muscle, spleen, thymus, Involved in vesicular transport in the osteoclast (By similarity), Involvement in disease:Defects in PLEKHM1 are the cause of osteopetrosis autosomal recessive type 6 (OPTB6), Tissue specificity: Expressed in placenta
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms KIAA0356
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPLEKHM1 Conjugated
Short name FITC Conjugated, PLEKHM1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PLEKHM1 (Antibody to)
Alternative techniqueantibodies
Identity 29017
Gene PLEKHM1
Long gene name pleckstrin homology and RUN domain containing M1
Synonyms gene name family M (with RUN domain) member 1 , pleckstrin homology domain containing
Locus 17q21, 31
Discovery year 2004-02-27
GenBank acession X85792
Entrez gene record 9842
Pubmed identfication 9205841 12820725
RefSeq identity NM_014798
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000179074

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