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PLK1 (18D4) Monoclonal Antibody

PLK1 (18D4) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePLK1 (18D4) Monoclonal Antibody
Also known asPLK1 (18D4) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPLK1
SpecificityThis is a highly specific antibody against PLK1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number18D4
Concentration2ug/ul
SourceRecombinant human protein purified from E, coli (GST/His-Plk1)
Gene ID number5347
Swiss ProtP53350
Tested Applications IP, WB
Recommended dilutions0ug), 0ug/mL) IP (5, WB (2
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At the onset of mitosis, Cdk1 (cyclin-dependent kinase 1) is known to phosphorylate Eg5, For example, Plk1, Plks are important regulators of the APC/C, Plks contribute to the activation of Cdk1-cyclinB, Several mitosis-specific protein kinases have been implicated in bipolar spindle assembly and chromosome biorientation, Sister chromatid separation and the subsequent formation of two genetically identical daughter cells depend on the symmetrical attachment of all chromosomes to the mitotic spindle, a key component of the ubiquitin-dependent proteolytic degradation pathway, a kinesin that is required for the migration of centrosomes and is thus needed for the formation of bipolar spindles, a process called chromosome biorientation, and cytokinesis, and they are also required for the inactivation of Cdk1 and exit from mitosis, has been implicated in regulating centrosome maturation, mitotic entry, sister chromatid cohesion, the anaphase-promoting complex/cyclosome (APC/C), the most studied Plk, Polo-like kinases (Plks) are important regulators of the cell cycle
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PLK-1, PLK1, Polo-like kinase 1, STPK13, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase PLK1, PLK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetPLK1 (18D4) Monoclonal
Short namePLK1 (18D4) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative namePLK1 (18D4) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 9077
Gene PLK1
Long gene name polo like kinase 1
Synonyms gene PLK
Synonyms gene name polo-like kinase (Drosophila) polo-like kinase 1
Locus 16p12, 2
Discovery year 1994-07-25
Entrez gene record 5347
Pubmed identfication 8127874
RefSeq identity NM_005030
Havana BLAST/BLAT OTTHUMG00000096984

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