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PLZF Antibody / ZBTB16

PLZF Antibody / ZBTB16 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPLZF / ZBTB16
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the PLZF antibody should be determined by the researcher
Intented useThis PLZF antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q05516
PurityAntigen affinity
Description Alternate transcriptional splice variants have been characterized, Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL), This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus, This protein is located in the nucleus, and interacts with a histone deacetylase, is involved in cell cycle progression, Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene
ImmunogenAmino acids M1-E165 from the human protein were used as the immunogen for the PLZF antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PLZF antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPLZF / ZBTB16
Short namePLZF Antibody / ZBTB16
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePLZF (Antibody to) / zinc finger and BTB domain containing 16
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0030097 and hemopoiesis and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0035136 and forelimb morphogenesis and biological process this GO :0035137 and hindlimb morphogenesis and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048133 and male germ-line stem cell division and biological process this GO :0051138 and positive regulation of NK T cell differentiation and biological process this GO :0051216 and cartilage development and biological process this GO :0061036 and positive regulation of cartilage development and biological process, PLZF and ZNF145, ZBTB16 and IDBG-630682 and ENSBTAG00000011266 and 534401, ZBTB16 and IDBG-72004 and ENSG00000109906 and 7704, Zbtb16 and IDBG-162201 and ENSMUSG00000066687 and 235320, metal ion binding, nuclei, this GO :0001501 and skeletal system development and biological process this GO :0001823 and mesonephros development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0019904: protein domain specific binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0046872: metal ion binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0019904: protein domain specific binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0046872: metal ion binding, zinc finger and BTB domain containing 16
Identity 12930
Gene ZBTB16
Long gene name zinc finger and BTB domain containing 16
Synonyms gene ZNF145
Synonyms gene name expressed in promyelocytic leukemia) , zinc finger protein 145 (Kruppel-like
Synonyms PLZF
Synonyms name promyelocytic leukaemia zinc finger
Locus 11q23, 2
Discovery year 1993-11-01
GenBank acession Z19002
Entrez gene record 7704
RefSeq identity NM_006006
Classification BTB domain containing Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000168243

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