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PMP22 Antibody, FITC Conjugated

PMP22 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PMP22 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPMP22
SpecificityThis is a highly specific antibody against PMP22
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range117-133/160
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PMP-22
Gene ID number5376
Swiss ProtQ01453
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alterations in the level of this protein cause several genetic human diseases, If one copy of the gene is deleted, If the protein is duplicated, In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration, patients develop Charcot Marie Tooth disease, they suffer from the inherited tendency to pressure palsies, PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PMP22
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPMP22 Conjugated
Short name FITC Conjugated, PMP22 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PMP22 (Antibody to)
Alternative techniqueantibodies
Identity 9716
Gene PXMP2
Long gene name peroxisomal membrane protein 2
Synonyms gene name 22kDa , peroxisomal membrane protein 2 (22kD) peroxisomal membrane protein 2
Locus 12q24, 33
Discovery year 1992-03-03
Entrez gene record 5827
Pubmed identfication 11590176
RefSeq identity NM_018663
Havana BLAST/BLAT OTTHUMG00000168019

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