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PNP/Nucleoside phosphorylase Antibody

PNP/Nucleoside phosphorylase Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePNP/Nucleoside phosphorylase Antibody
Also known asPNP/Nucleoside phosphorylase Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPNP/Nucleoside phosphorylase
SpecificityThis is a highly specific antibody against PNP/Nucleoside phosphorylase
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PNP/Nucleoside phosphorylase
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Children with PNP deficiency are highly prone to infections, Human PNP catalyzes the reversible phosphorolysis of ribonucleosides and 2â, It belongs to the PNP/MTAP phosphorylase family of proteins, PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, also designated inosine phosphorylase, and cancer, and their analogs, autoimmune disorders, comprising four percent of combined immunodeficiency cases, forms a homotrimer, hypoxanthine, neurological impairment, &euro, &trade, -deoxyribonucleosides with specificity for guanine, Purine nucleoside phosphorylase (PNP)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLJ94043, FLJ97288, MGC117396, MGC125915, MGC125916, NP, Np1, Nucleoside phosphorylase, PNP, PNPH_HUMAN, PRO1837, PUNP, Pnp1, Purine nucleoside orthophosphate ribosyltransferase, Purine nucleoside phosphorylase, Inosine phosphorylase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPNP/Nucleoside phosphorylase
Short namePNP/Nucleoside phosphorylase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namepurine nucleoside phosphorylase/Nucleoside phosphorylase (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, NP and PRO1837 and PUNP, PNP and IDBG-2272 and ENSG00000198805 and 4860, phosphate ion binding, this GO :0001882 and nucleoside binding and molecular function this GO :0002060 and purine nucleobase binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004731 and purine-nucleoside phosphorylase activity and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006139 and nucleobase-containing compound metabolic process and biological process this GO :0006144 and purine nucleobase metabolic process and biological process this GO :0006148 and inosine catabolic process and biological process this GO :0006195 and purine nucleotide catabolic process and biological process this GO :0006738 and nicotinamide riboside catabolic process and biological process this GO :0006955 and immune response and biological process this GO :0008144 and drug binding and molecular function this GO :0009116 and nucleoside metabolic process and biological process this GO :0034356 and NAD biosynthesis via nicotinamide riboside salvage pathway and biological process this GO :0034418 and urate biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042301 and phosphate ion binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043101 and purine-containing compound salvage and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070970 and interleukin-2 secretion and biological process, this GO :0001882: nucleoside binding, this GO :0001882: nucleoside binding and also this GO :0002060: purine nucleobase binding and also this GO :0003824: catalytic activity and also this GO :0004731: purine-nucleoside phosphorylase activity and also this GO :0008144: drug binding and also this GO :0042301: phosphate ion binding, this GO :0002060: purine nucleobase binding, this GO :0003824: catalytic activity, this GO :0004731: purine-nucleoside phosphorylase activity, this GO :0008144: drug binding, this GO :0042301: phosphate ion binding, purine nucleoside phosphorylase
Identity 9327
Gene PPY
Long gene name pancreatic polypeptide
Synonyms PNP
Synonyms name pancreatic polypeptide Y prepro-PP (prepropancreatic polypeptide)
Locus 17q21, 31
Discovery year 1986-01-01
Entrez gene record 5539
Pubmed identfication 3753985
RefSeq identity NM_002722
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000181800

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