Filters

PNPT1 Antibody, ALEXA FLUOR 488

PNPT1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, PNPT1 Polyclonal Antibody
Also known asAnti-PNPT1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPNPT1
SpecificityThis is a highly specific antibody against PNPT1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range570-620/783
Subcellular location Mitochondrion, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PNPT1
Gene ID Number87178
Swiss ProtQ8TCS8
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binds to the RNA subunit of ribonuclease P, Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction, Component of the mitochondrial degradosome (mtEXO) complex, In the cytoplasm, MRP RNA and miR-221 microRNA, Mitochondrial intermembrane factor with RNA-processing exoribonulease activity, Plays a role as a cytoplasmic RNA import factor that mediates the translocation of small RNA components, Plays a role in mitochondrial morphogenesis and respiration, Plays also a role in RNA cell surveillance by cleaning up oxidized RNAs, Regulates the stability of specific mature miRNAs in melanoma cells, Required for correct processing and polyadenylation of mitochondrial mRNAs, degrades c-myc mRNA upon treatment with IFNB1/IFN-beta, into the mitochondrial matrix, like the 5S RNA, preferentially, regulates the expression of the electron transport chain (ETC) components at the mRNA and protein levels, resulting in a growth arrest in melanoma cells, shows a 3'-to-5' exoribonuclease mediating mRNA degradation activity, specifically and selectively degrades miR-221, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner, the RNA subunit of ribonuclease P and the mitochondrial RNA-processing (MRP) RNA, RNA-binding protein implicated in numerous RNA metabolic processes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms PNPase OLD35 old-35
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PNPT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPNPT1
Short namePNPT1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, PNPT1 (Antibody to)
Alternative techniqueantibodies
Identity 23166
Gene PNPT1
Long gene name polyribonucleotide nucleotidyltransferase 1
Synonyms gene DFNB70
Synonyms gene name autosomal recessive 70 , deafness
Synonyms name RNA exonuclease , polynucleotide phosphorylase 3', -5'
Locus 2p16, 1
Discovery year 2003-09-25
GenBank acession BC053660
Entrez gene record 87178
Pubmed identfication 12419256
RefSeq identity NM_033109
Classification Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000129335

Similar products

Subscribe to our Newsletter