PNPT1 Antibody, FITC Conjugated

PNPT1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	FITC Conjugated, PNPT1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Anti-FITC Antibody
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	PNPT1
Specificity	This is a highly specific antibody against PNPT1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	570-620/783
Subcellular location	Mitochondrion, Cytoplasm
Source	KLH conjugated synthetic peptide derived from human PNPT1
Gene ID number	87178
Swiss Prot	Q8TCS8
Tested applications	IF(IHC-P)
Recommended dilutions	IF(IHC-P)(1:50-200)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Binds to the RNA subunit of ribonuclease P, Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction, Component of the mitochondrial degradosome (mtEXO) complex, In the cytoplasm, MRP RNA and miR-221 microRNA, Mitochondrial intermembrane factor with RNA-processing exoribonulease activity, Plays a role as a cytoplasmic RNA import factor that mediates the translocation of small RNA components, Plays a role in mitochondrial morphogenesis and respiration, Plays also a role in RNA cell surveillance by cleaning up oxidized RNAs, Regulates the stability of specific mature miRNAs in melanoma cells, Required for correct processing and polyadenylation of mitochondrial mRNAs, degrades c-myc mRNA upon treatment with IFNB1/IFN-beta, into the mitochondrial matrix, like the 5S RNA, preferentially, regulates the expression of the electron transport chain (ETC) components at the mRNA and protein levels, resulting in a growth arrest in melanoma cells, shows a 3'-to-5' exoribonuclease mediating mRNA degradation activity, specifically and selectively degrades miR-221, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner, the RNA subunit of ribonuclease P and the mitochondrial RNA-processing (MRP) RNA, RNA-binding protein implicated in numerous RNA metabolic processes
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	494nm/518nm
Synonyms	PNPase OLD35 old-35
Properties	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	PNPT1 Conjugated
Short name	FITC Conjugated, PNPT1 Antibody
Technique	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	FITC
Alternative name	fluorecein coupled, PNPT1 (Antibody to)
Alternative technique	antibodies
Identity	23166
Gene	PNPT1
Long gene name	polyribonucleotide nucleotidyltransferase 1
Synonyms gene	DFNB70
Synonyms gene name	autosomal recessive 70 , deafness
Synonyms name	RNA exonuclease , polynucleotide phosphorylase 3', -5'
Locus	2p16, 1
Discovery year	2003-09-25
GenBank acession	BC053660
Entrez gene record	87178
Pubmed identfication	12419256
RefSeq identity	NM_033109
Classification	Deafness associated genes
Havana BLAST/BLAT	OTTHUMG00000129335

PNPT1 Antibody, FITC Conjugated

PNPT1 Antibody, FITC Conjugated size: 0.1ml 333

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