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Podocalyxin Antibody

Podocalyxin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePodocalyxin Primary Polyclonal Antibody
Also known asPodocalyxin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPodocalyxin
SpecificityThis is a highly specific antibody against Podocalyxin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range526-558/558
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Podocalyxin
Gene ID number5420
Swiss ProtO00592
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a pro-adhesive molecule, Affects EZR-dependent signaling events, Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion, Induces the formation of apical actin-dependent microvilli, Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis, Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner, leading to increased activities of the MAPK and PI3K pathways in cancer cells, Involved in the regulation of both adhesion and cell morphology and cancer progression
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GCTM-2 antigen, Gp2, PCLP, PCLP-1, PCLP1, PODXL, Podocalyxin, Podocalyxin-like protein 1, PC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPodocalyxin
Short namePodocalyxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePodocalyxin (Antibody to)
Alternative techniqueantibodies
Identity 17936
Gene PODXL2
Long gene name podocalyxin like 2
Synonyms gene name podocalyxin-like 2
Synonyms PODLX2 endoglycan
Synonyms name endoglycan
Locus 3q21, 3
Discovery year 2004-07-21
GenBank acession AF219137
Entrez gene record 50512
Pubmed identfication 10722749
RefSeq identity NM_015720
Havana BLAST/BLAT OTTHUMG00000159642

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