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PODXL (632CT5.11.4) Monoclonal Antibody

PODXL (632CT5.11.4) Monoclonal Antibody size: 0.1ml 328

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 328
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name11, 4) Monoclonal Antibody, PODXL (632CT5
Also known as11, 4) Monoclonal Antibody, PODXL (632CT5
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPODXL
SpecificityThis is a highly specific antibody against PODXL
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number4, 11, 632CT5
SourceThis PODXL antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL
Gene ID number5420
Swiss ProtO00592
Tested Applications IF, WB
Recommended dilutions WB(1:500-5000), IF(1:100)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a pro-adhesive molecule, Affects EZR-dependent signaling events, Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion, Induces the formation of apical actin-dependent microvilli, Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis, Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner, leading to increased activities of the MAPK and PI3K pathways in cancer cells, Involved in the regulation of both adhesion and cell morphology and cancer progression
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GCTM-2 antigen, Gp200, PCLP, PCLP-1, PCLP1, PODXL, Podocalyxin, Podocalyxin-like protein 1, PC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target11, 4) Monoclonal, PODXL (632CT5
Short name11, 4) Monoclonal Antibody, PODXL (632CT5
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name11, 4) monoclonal (Antibody to), podocalyxin-like (632CT5
Alternative techniqueantibodies
Alternative to gene target Extracellular, Gp200 and PC and PCLP and PCLP-1, PODXL and IDBG-41798 and ENSG00000128567 and 5420, PODXL and IDBG-635552 and ENSBTAG00000010452 and 616366, Podxl and IDBG-133888 and ENSMUSG00000025608 and 27205, protein binding, this GO :0001726 and ruffle and cellular component this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030175 and filopodium and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0031528 and microvillus membrane and cellular component this GO :0032534 and regulation of microvillus assembly and biological process this GO :0033634 and positive regulation of cell-cell adhesion mediated by integrin and biological process this GO :0036057 and slit diaphragm and cellular component this GO :0044297 and cell body and cellular component this GO :0045121 and membrane raft and cellular component this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072015 and glomerular visceral epithelial cell development and biological process this GO :0072175 and epithelial tube formation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, podocalyxin-like
Identity 9171
Gene PODXL
Long gene name podocalyxin like
Synonyms gene name podocalyxin-like
Synonyms PCLP Gp200 PC
Locus 7q32, 3
Discovery year 1997-07-11
Entrez gene record 5420
RefSeq identity NM_001018111
Havana BLAST/BLAT OTTHUMG00000154918

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