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POLR3C Antibody

POLR3C Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePOLR3C Primary Polyclonal Antibody
Also known asPOLR3C PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPOLR3C
SpecificityThis is a highly specific antibody against POLR3C
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range50-80/534
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human POLR3C
Gene ID number10623
Swiss ProtQ9BUI4
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as nuclear and cytosolic DNA sensor involved in innate immune response, Can sense non-self dsDNA that serves as template for transcription into dsRNA, May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F, Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses, Specific core component of RNA polymerase III which synthesizes small RNAs, The non-self RNA polymerase III transcripts, or in stimulating catalytic functions of other subunits during initiation, such as 5S rRNA and tRNAs, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway, DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA-directed RNA polymerase III subunit C, DNA-directed RNA polymerase III subunit RPC3, POLR3C, RNA polymerase III 62 kDa subunit, RNA polymerase III subunit C3, RPC62, RPC3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPOLR3C
Short namePOLR3C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namepolymerase (RNA) III (Desoxyribonucleic acid directed) polypeptide C (62kD) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-directed RNA polymerase activity, DNA-templated and biological process this GO :0006359 and regulation of transcription from RNA polymerase III promoter and biological process this GO :0006383 and transcription from RNA polymerase III promoter and biological process this GO :0006385 and transcription elongation from RNA polymerase III promoter and biological process this GO :0006386 and termination of RNA polymerase III transcription and biological process this GO :0010467 and gene expression and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0051607 and defense response to virus and biological process, POLR3C and IDBG-101761 and ENSG00000186141 and 102724798, POLR3C and IDBG-633711 and ENSBTAG00000021637 and 507314, Polr3c and IDBG-176295 and ENSMUSG00000028099 and 74414, RPC3 and RPC62, nuclei, this GO :0001056 and RNA polymerase III activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003899 and DNA-directed RNA polymerase activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005666 and DNA-directed RNA polymerase III complex and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0001056: RNA polymerase III activity, this GO :0001056: RNA polymerase III activity and also this GO :0003677: DNA binding and also this GO :0003899: DNA-directed RNA polymerase activity, this GO :0003677: DNA binding, this GO :0003899: DNA-directed RNA polymerase activity, 10623, polymerase (RNA) III (DNA directed) polypeptide C (62kD)
Identity 30076
Gene POLR3C
Long gene name RNA polymerase III subunit C
Synonyms gene name polymerase (RNA) III (DNA directed) polypeptide C (62kD)
Synonyms RPC62 RPC3
Locus 1q21, 1
Discovery year 2004-04-21
GenBank acession AJ238234
Entrez gene record 10623
Pubmed identfication 9171375 12391170
RefSeq identity NM_006468
Classification RNA polymerase subunits
Havana BLAST/BLAT OTTHUMG00000013753

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