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Polycystin 1 Antibody

Polycystin 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePolycystin 1 Primary Polyclonal Antibody
Also known asPolycystin 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPolycystin 1
SpecificityThis is a highly specific antibody against Polycystin 1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range131-180/4303
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Polycystin 1
Gene ID number5310
Swiss ProtP98161
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a regulator of cilium length, Involved in adhesive protein-protein and protein-carbohydrate interactions, Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium, May be an ion-channel regulator, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, leads to cilium shortening and thus decreases flow-induced signaling (By similarity), together with PKD2, which decreases intracellular cAMP, Involved in renal tubulogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Autosomal dominant polycystic kidney disease 1 protein, PKD1, Pc-1, Polycystin-1, TRPP1, PBP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPolycystin 1
Short namePolycystin 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePolycystin 1 (Antibody to)
Alternative techniqueantibodies
Identity 21716
Gene PKD1L3
Long gene name polycystin 1 like 3, transient receptor potential channel interacting
Synonyms gene name polycystic kidney disease 1-like 3
Locus 16q22, 2
Discovery year 2003-08-05
GenBank acession AY164485
Entrez gene record 342372
Pubmed identfication 12782129 20538909
RefSeq identity NM_181536
Classification C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000166114

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