Name : Polycystin 1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7436303309
| Long name | ALEXA FLUOR 488 Conjugated, Polycystin 1 Polyclonal Antibody |
| Also known as | Anti-Polycystin 1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Polycystin 1 |
| Specificity | This is a highly specific antibody against Polycystin 1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 131-180/4303 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Polycystin 1 |
| Gene ID Number | 5310 |
| Swiss Prot | P98161 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a regulator of cilium length, Involved in adhesive protein-protein and protein-carbohydrate interactions, Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium, May be an ion-channel regulator, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, leads to cilium shortening and thus decreases flow-induced signaling (By similarity), together with PKD2, which decreases intracellular cAMP, Involved in renal tubulogenesis |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Polycystin 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Polycystin 1 |
| Short name | Polycystin 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Polycystin 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21716 |
| Gene | PKD1L3 |
| Long gene name | polycystin 1 like 3, transient receptor potential channel interacting |
| Synonyms gene name | polycystic kidney disease 1-like 3 |
| Locus | 16q22, 2 |
| Discovery year | 2003-08-05 |
| GenBank acession | AY164485 |
| Entrez gene record | 342372 |
| Pubmed identfication | 12782129 20538909 |
| RefSeq identity | NM_181536 |
| Classification | C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166114 |