| Long name | POMC Primary Polyclonal Antibody |
| Also known as | POMC PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | POMC |
| Specificity | This is a highly specific antibody against POMC |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 237-267/267 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human POMC |
| Gene ID number | 5443 |
| Swiss Prot | P01189 |
| Tested Applications | FCM, IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Beta-endorphin and Met-enkephalin are endogenous opiates, MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes, ACTH stimulates the adrenal glands to release cortisol |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACTH, CLIP, Corticotropin-lipotropin, MSH, NPP, POC, POMC, Pro-opiomelanocortin, LPH |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | POMC |
| Short name | POMC Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | proopiomelanocortin (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ACTH and CLIP and LPH and MSH and NPP and POC, Extracellular, POMC and IDBG-34380 and ENSG00000115138 and 5443, POMC and IDBG-637211 and ENSBTAG00000007897 and 281416, Pomc and IDBG-127850 and ENSMUSG00000020660 and 18976, this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0007165 and signal transduction and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0016486 and peptide hormone processing and biological process this GO :0030141 and secretory granule and cellular component this GO :0031781 and type 3 melanocortin receptor binding and molecular function this GO :0031782 and type 4 melanocortin receptor binding and molecular function this GO :0032098 and regulation of appetite and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0033059 and cellular pigmentation and biological process this GO :0034774 and secretory granule lumen and cellular component this GO :0042593 and glucose homeostasis and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0070873 and regulation of glycogen metabolic process and biological process this GO :0070996 and type 1 melanocortin receptor binding and molecular function this GO :2000852 and regulation of corticosterone secretion and biological process, this GO :0001664: G-protein coupled receptor binding, this GO :0001664: G-protein coupled receptor binding and also this GO :0005102: receptor binding and also this GO :0005179: hormone activity and also this GO :0031781: type 3 melanocortin receptor binding and also this GO :0031782: type 4 melanocortin receptor binding and also this GO :0070996: type 1 melanocortin receptor binding, this GO :0005102: receptor binding, this GO :0005179: hormone activity, this GO :0031781: type 3 melanocortin receptor binding, this GO :0031782: type 4 melanocortin receptor binding, this GO :0070996: type 1 melanocortin receptor binding, type 1 melanocortin receptor binding, proopiomelanocortin |
| Identity | 9201 |
| Gene | POMC |
| Long gene name | proopiomelanocortin |
| Synonyms | MSH POC CLIP ACTH NPP LPH |
| Synonyms name | adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin adrenocorticotropic hormone opiomelanocortin prepropeptide |
| Locus | 2p23, 3 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 5443 |
| Pubmed identfication | 6254047 9620771 |
| RefSeq identity | NM_001035256 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000094764 |
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