Filters

POMT1 Antibody

POMT1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePOMT1 Primary Polyclonal Antibody
Also known asPOMT1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPOMT1
SpecificityThis is a highly specific antibody against POMT1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human POMT1
Gene ID number10585
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), Enzymatic activity is dependent on co expression of POMT1 with POMT2, Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours, Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues, Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction, a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life, which is associated with mild mental retardation, POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein O-mannosyl-transferase 1, POMT1_HUMAN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPOMT1
Short namePOMT1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePOMT1 (Antibody to)
Alternative techniqueantibodies
Identity 9202
Gene POMT1
Long gene name protein O-mannosyltransferase 1
Synonyms LGMD2K
Synonyms name dolichyl-phosphate-mannose-protein mannosyltransferase
Locus 9q34, 13
Discovery year 1999-06-25
GenBank acession AF095136
Entrez gene record 10585
Pubmed identfication 10366449
RefSeq identity NM_007171
Classification Dolichyl D-mannosyl phosphate dependent mannosyltransferases
Havana BLAST/BLAT OTTHUMG00000020826
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_842

Similar products

Subscribe to our Newsletter