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POMT1 Antibody, ALEXA FLUOR 488

POMT1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, POMT1 Polyclonal Antibody
Also known asAnti-POMT1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPOMT1
SpecificityThis is a highly specific antibody against POMT1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human POMT1
Gene ID Number10585
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), Enzymatic activity is dependent on co expression of POMT1 with POMT2, Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours, Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues, Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction, a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life, which is associated with mild mental retardation, POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms LGMD2K
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the POMT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPOMT1
Short namePOMT1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, POMT1 (Antibody to)
Alternative techniqueantibodies
Identity 9202
Gene POMT1
Long gene name protein O-mannosyltransferase 1
Synonyms name dolichyl-phosphate-mannose-protein mannosyltransferase
Locus 9q34, 13
Discovery year 1999-06-25
GenBank acession AF095136
Entrez gene record 10585
Pubmed identfication 10366449
RefSeq identity NM_007171
Classification Dolichyl D-mannosyl phosphate dependent mannosyltransferases
Havana BLAST/BLAT OTTHUMG00000020826
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_842

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