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POMT1 Antibody, Cy5.5 Conjugated

POMT1 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, POMT1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPOMT1
SpecificityThis is a highly specific antibody against POMT1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human POMT1
Gene ID number10585
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), Enzymatic activity is dependent on co expression of POMT1 with POMT2, Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours, Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues, Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction, a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life, which is associated with mild mental retardation, POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms LGMD2K
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetPOMT1 Conjugated
Short name Conjugated, POMT1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, POMT1 (Antibody to)
Alternative techniqueantibodies
Identity 9202
Gene POMT1
Long gene name protein O-mannosyltransferase 1
Synonyms name dolichyl-phosphate-mannose-protein mannosyltransferase
Locus 9q34, 13
Discovery year 1999-06-25
GenBank acession AF095136
Entrez gene record 10585
Pubmed identfication 10366449
RefSeq identity NM_007171
Classification Dolichyl D-mannosyl phosphate dependent mannosyltransferases
Havana BLAST/BLAT OTTHUMG00000020826
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_842

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