Name : POMT1 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7307229543
| Long name | Cy5, 5 Conjugated, POMT1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | POMT1 |
| Specificity | This is a highly specific antibody against POMT1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human POMT1 |
| Gene ID number | 10585 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), Enzymatic activity is dependent on co expression of POMT1 with POMT2, Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours, Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues, Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction, a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life, which is associated with mild mental retardation, POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | LGMD2K |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | POMT1 Conjugated |
| Short name | Conjugated, POMT1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, POMT1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9202 |
| Gene | POMT1 |
| Long gene name | protein O-mannosyltransferase 1 |
| Synonyms name | dolichyl-phosphate-mannose-protein mannosyltransferase |
| Locus | 9q34, 13 |
| Discovery year | 1999-06-25 |
| GenBank acession | AF095136 |
| Entrez gene record | 10585 |
| Pubmed identfication | 10366449 |
| RefSeq identity | NM_007171 |
| Classification | Dolichyl D-mannosyl phosphate dependent mannosyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000020826 |
| Locus Specific Databases | Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_842 |