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PP1B (AF9B12) Monoclonal Antibody

PP1B (AF9B12) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePP1B (AF9B12) Monoclonal Antibody
Also known asPP1B (AF9B12) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPP1B
SpecificityThis is a highly specific antibody against PP1B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone numberAF9B12
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli (His-PP1B)
Gene ID number5500
Swiss ProtP62140
Tested ApplicationsWB
Recommended dilutions2 ug/ml), WB (0
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Component of the PTW/PP1 phosphatase complex, Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, In balance with CSNK1D and CSNK1E, Involved in regulation of ionic conductances and long-term synaptic plasticity, May dephosphorylate CSNK1D and CSNK1E, Protein phosphatase (PP1) is essential for cell division, determines the circadian period length, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208), through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase, Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HEL-S-80p, PP-1B, PP1beta, PPP1CB, PPP1CD, Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP1B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetPP1B (AF9B12) Monoclonal
Short namePP1B (AF9B12) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative namePP1B (AF9B12) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 9282
Gene PPP1CB
Long gene name protein phosphatase 1 catalytic subunit beta
Synonyms gene name beta isoform protein phosphatase 1, beta isozyme , catalytic subunit, catalytic subunit, protein phosphatase 1
Synonyms PP1B PP-1B PP1beta
Locus 2p23, 2
Discovery year 1993-01-22
Entrez gene record 5500
Pubmed identfication 8312365
Classification Protein phosphatase catalytic subunits
Havana BLAST/BLAT OTTHUMG00000152011

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