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PP2A alpha + beta Antibody, Biotin Conjugated

PP2A alpha + beta Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, PP2A alpha + beta Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPP2A alpha + beta
SpecificityThis is a highly specific antibody against PP2A alpha + beta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range267-309/309
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human PP-2A
Gene ID number5515
Swiss ProtP67775
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates RAF1 by dephosphorylating it at 'Ser-259', Can dephosphorylate SV4 large T antigen and p53/TP53, Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity), PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, and MAP-2 kinase, mitogen-stimulated S6 kinase, PP2A is the major phosphatase for microtubule-associated proteins (MAPs)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, PPP2CA, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, RP-C
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPP2A alpha + beta Conjugated
Short name Conjugated, PP2A alpha + beta Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PP2A a and b (Antibody to)
Alternative techniqueantibodies

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