Name : PP2CA Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2338512223
| Long name | ALEXA FLUOR 488 Conjugated, PP2CA Polyclonal Antibody |
| Also known as | Anti-PP2CA PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PP2CA |
| Specificity | This is a highly specific antibody against PP2CA |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PP2CA |
| Gene ID Number | 5494 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses, Jul 2008], MAP kinases and MAP kinase kinases, Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, PP2C family members are known to be negative regulators of cell stress response pathways, This phosphatase can also dephosphorylate cyclin-dependent kinases, This phosphatase dephosphorylates, Three alternatively spliced transcript variants encoding distinct isoforms have been described, [provided by RefSeq, and negatively regulates the activities of, and thus may be involved in cell cycle control, which leads to G2/M cell cycle arrest and apoptosis, The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | MGC9201 PP2Calpha PP2CA |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PP2CA Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | PP2CA |
| Short name | PP2CA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, PP2CA (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9275 |
| Gene | PPM1A |
| Long gene name | Mg2+/Mn2+ dependent 1A , protein phosphatase |
| Synonyms gene name | 1A , Mg2+/Mn2+ dependent, alpha isoform protein phosphatase, magnesium-dependent, protein phosphatase 1A (formerly 2C) |
| Synonyms name | alpha isoform , phosphatase 2C alpha protein phosphatase 2C |
| Locus | 14q23, 1 |
| Discovery year | 1993-02-05 |
| GenBank acession | S87759 |
| Entrez gene record | 5494 |
| Pubmed identfication | 1311954 |
| RefSeq identity | NM_021003 |
| Classification | Mg2+/Mn2+ dependent , Protein phosphatases |
| Havana BLAST/BLAT | OTTHUMG00000140333 |