Name : PPAPDC3 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9772248742
| Long name | FITC Conjugated, PPAPDC3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PPAPDC3 |
| Specificity | This is a highly specific antibody against PPAPDC3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PPAPDC3 |
| Gene ID number | 84814 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Has no detectable enzymatic activity, It is a member of the PAP2 superfamily of phosphatases and haloperoxidases, Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis, PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR, PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues, also known as nuclear envelope transmembrane protein 39 (NET39), in part through effects on MTOR signaling, was initially discovered in an in silico screen for secreted or membrane proteins, PPAPDC3, Plays a role as negative regulator of myoblast differentiation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | MGC12921 FLJ14662 NET39 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PPAPDC3 Conjugated |
| Short name | FITC Conjugated, PPAPDC3 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PPAPDC3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28174 |
| Gene | PLPP7 |
| Long gene name | phospholipid phosphatase 7 (inactive) |
| Synonyms gene | C9orf67 PPAPDC3 |
| Synonyms gene name | chromosome 9 open reading frame 67 phosphatidic acid phosphatase type 2 domain containing 3 |
| Synonyms name | nuclear envelope transmembrane protein NET39 |
| Locus | 9q34, 13 |
| Discovery year | 2004-01-06 |
| GenBank acession | AK027568 |
| Entrez gene record | 84814 |
| Pubmed identfication | 12958361 |
| RefSeq identity | NM_032728 |
| Classification | Phospholipid phosphatases |
| Havana BLAST/BLAT | OTTHUMG00000020822 |