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PPAR alpha (Ser12) Antibody, FITC Conjugated

PPAR alpha (Ser12) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PPAR alpha (Ser12) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPPAR alpha Ser12
SpecificityThis is a highly specific antibody against PPAR alpha Ser12
ModificationPhosphorylation
Modification siteSer12
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1-15/468
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12
Gene ID number5465
Swiss ProtQ07869
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activated by oleylethanolamide, Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC), Functions as transcription activator for the ACOX1 and P450 genes, Key regulator of lipid metabolism, May be required for the propagation of clock information to metabolic pathways regulated by PER2, Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids, Regulates the peroxisomal beta-oxidation pathway of fatty acids, Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2, a naturally occurring lipid that regulates satiety, Ligand-activated transcription factor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms hPPAR NR1C1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPPAR alpha (Ser12) Conjugated
Short name FITC Conjugated, PPAR alpha (Ser12) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PPAR a (Ser12) (Antibody to)
Alternative techniqueantibodies
Identity 9232
Gene PPARA
Long gene name peroxisome proliferator activated receptor alpha
Synonyms gene PPAR
Synonyms gene name alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor
Locus 22q13, 31
Discovery year 1993-11-01
GenBank acession L02932
Entrez gene record 5465
Pubmed identfication 7684926 10591208
RefSeq identity NM_001001928
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000150443

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