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PPP4C Antibody

PPP4C Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePPP4C Primary Polyclonal Antibody
Also known asPPP4C PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPPP4C
SpecificityThis is a highly specific antibody against PPP4C
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range260-307/307
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PP4C
Gene ID number5531
Swiss ProtP60510
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DNA damage checkpoint signaling, DNA repair, Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity), In response to DNA damage, NF-kappa-B activation and cell migration, The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3, The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-14 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair, activation of c-Jun N-terminal kinase MAPK8, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin, apoptosis, catalyzes RPA2 dephosphorylation, maturation of spliceosomal snRNPs, regulation of histone acetylation, tumor necrosis factor (TNF)-alpha signaling, Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PP-X, PP4C, PPH3, PPP4, PPP4C, PPX, Protein phosphatase X, Serine/threonine-protein phosphatase 4 catalytic subunit, PP4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPPP4C
Short namePPP4C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePPP4C (Antibody to)
Alternative techniqueantibodies
Identity 9319
Gene PPP4C
Long gene name protein phosphatase 4 catalytic subunit
Synonyms gene name catalytic subunit , catalytic subunit protein phosphatase 4, protein phosphatase 4 (formerly X)
Synonyms PP4 PPX
Synonyms name catalytic subunit , protein phosphatase X
Locus 16p11, 2
Discovery year 1993-01-22
Entrez gene record 5531
Pubmed identfication 9177794
RefSeq identity NM_002720
Classification Protein phosphatase catalytic subunits
Havana BLAST/BLAT OTTHUMG00000132113

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