Name : PQBP1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1513170521
| Long name | FITC Conjugated, PQBP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PQBP1 |
| Specificity | This is a highly specific antibody against PQBP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PQBP1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i, PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling, PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, The human PQBP-1 gene maps to chromosome Xp11, androgen receptor and Brain-2), cerebellar cortex and olfactory bulb, huntingtin, with abundant levels in hippocampus, 23, Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders, e |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PQBP1 Conjugated |
| Short name | FITC Conjugated, PQBP1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PQBP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9330 |
| Gene | PQBP1 |
| Long gene name | polyglutamine binding protein 1 |
| Synonyms gene | RENS1 MRXS8 SHS MRX55 MRX2 MRXS3 |
| Synonyms gene name | Sutherland-Haan X-linked mental retardation syndrome mental retardation, X-linked 2 (non-dysmorphic) , X-linked 55 mental retardation |
| Locus | Xp11, 23 |
| Discovery year | 1999-01-12 |
| GenBank acession | AJ005893 |
| Entrez gene record | 10084 |
| Pubmed identfication | 9875212 15024694 14634649 |
| RefSeq identity | NM_001032381, 1 |
| Classification | X-linked mental retardation |
| Havana BLAST/BLAT | OTTHUMG00000024128 |
| Locus Specific Databases | Mental Retardation database |