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PRAM1 Antibody

PRAM1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePRAM1 Primary Polyclonal Antibody
Also known asPRAM1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPRAM1
SpecificityThis is a highly specific antibody against PRAM1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRAM1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis, PRAM-1 demonstrates expression in hematopoietic tissues and lung, PRAM-1 expression is hindered by expression of PML-RAR-a, The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs, The retinoic acid-induced gene, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells, Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM, PRAM 1, PRAM-1, PRAM1, PRAM_HUMAN, PML RAR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPRAM1
Short namePRAM1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name alpha regulated adaptor molecule 1 (Antibody to), promyelocytic leukemia-retinoic acid receptor
Alternative techniqueantibodies
Alternative to gene target PRAM1 and IDBG-24943 and ENSG00000133246 and 84106, PRAM1 and IDBG-643837 and ENSBTAG00000021041 and 504848, Pram1 and IDBG-167526 and ENSMUSG00000032739 and 378460, lipid binding, multiple, this GO :0005515 and protein binding and molecular function this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008289 and lipid binding and molecular function this GO :0043313 and regulation of neutrophil degranulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008289: lipid binding, this GO :0008289: lipid binding, PML-RARA regulated adaptor molecule 1
Identity 30091
Gene PRAM1
Long gene name PML-RARA regulated adaptor molecule 1
Synonyms PML-RAR
Locus 19p13, 2
Discovery year 2005-07-04
GenBank acession BC028012
Entrez gene record 84106
Pubmed identfication 11301322 15572693
RefSeq identity NM_032152
Havana BLAST/BLAT OTTHUMG00000167924

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