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PRAM1 Antibody, Biotin Conjugated

PRAM1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, PRAM1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPRAM1
SpecificityThis is a highly specific antibody against PRAM1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PRAM1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis, PRAM-1 demonstrates expression in hematopoietic tissues and lung, PRAM-1 expression is hindered by expression of PML-RAR-a, The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs, The retinoic acid-induced gene, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells, Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PML-RAR
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPRAM1 Conjugated
Short name Conjugated, PRAM1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name alpha regulated adaptor molecule 1 (Antibody to), biotinilated coupled, promyelocytic leukemia-retinoic acid receptor
Alternative techniqueantibodies
Alternative to gene target PRAM1 and IDBG-24943 and ENSG00000133246 and 84106, PRAM1 and IDBG-643837 and ENSBTAG00000021041 and 504848, Pram1 and IDBG-167526 and ENSMUSG00000032739 and 378460, lipid binding, multiple, this GO :0005515 and protein binding and molecular function this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008289 and lipid binding and molecular function this GO :0043313 and regulation of neutrophil degranulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008289: lipid binding, this GO :0008289: lipid binding, PML-RARA regulated adaptor molecule 1
Identity 30091
Gene PRAM1
Long gene name PML-RARA regulated adaptor molecule 1
Locus 19p13, 2
Discovery year 2005-07-04
GenBank acession BC028012
Entrez gene record 84106
Pubmed identfication 11301322 15572693
RefSeq identity NM_032152
Havana BLAST/BLAT OTTHUMG00000167924

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