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PRAM1 Antibody / PML-RARA-regulated adapter molecule 1
PRAM1 Antibody / PML-RARA-regulated adapter molecule 1 size: 0.05 ml 199
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NJS POLY
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199
Size
0.05 ml
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| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | PRAM1 / PML-RARA-regulated adapter molecule 1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | Western blot: 1:500-1000 |
| Intented use | This PRAM1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 84106 |
| Uniprot # | Q96QH2 |
| Purity | Antigen affinity |
| Description | Binds to PtdIns(4)P, May be involved in integrin signaling in neutrophils, PML-RARA-regulated adapter molecule 1 may be involved in myeloid differentiation |
| Immunogen | A portion of amino acids 587-618 from the human protein was used as the immunogen for the PRAM1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PRAM1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | PRAM1 / PML-RARA-regulated adapter molecule 1 |
| Short name | PRAM1 Antibody / PML-RARA-regulated adapter molecule 1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | alpha regulated adaptor molecule 1 (Antibody to) / promyelocytic leukemia-retinoic acid receptor, alpha-regulated adapter molecule 1, promyelocytic leukemia-retinoic acid receptor |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007281 and germ cell development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007565 and female pregnancy and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008144 and drug binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009986 and cell surface and cellular component this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0030520 and intracellular estrogen receptor signaling pathway and biological process this GO :0030850 and prostate gland development and biological process this GO :0030852 and regulation of granulocyte differentiation and biological process this GO :0030853 and negative regulation of granulocyte differentiation and biological process this GO :0031076 and embryonic camera-type eye development and biological process this GO :0031490 and chromatin DNA binding and molecular function this GO :0031641 and regulation of myelination and biological process this GO :0032355 and response to estradiol and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032736 and positive regulation of interleukin-13 production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0032754 and positive regulation of interleukin-5 production and biological process this GO :0033189 and response to vitamin A and biological process this GO :0034097 and response to cytokine and biological process this GO :0035014 and phosphatidylinositol 3-kinase regulator activity and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043422 and protein kinase B binding and molecular function this GO :0043551 and regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044323 and retinoic acid-responsive element binding and molecular function this GO :0045471 and response to ethanol and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045630 and positive regulation of T-helper 2 cell differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006605 and protein targeting and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006977 and DNA damage response, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0050821 and protein stabilization and biological process this GO :0050897 and cobalt ion binding and molecular function this GO :0051457 and maintenance of protein location in nucleus and biological process this GO :0051607 and defense response to virus and biological process this GO :0051974 and negative regulation of telomerase activity and biological process this GO :0060058 and positive regulation of apoptotic process involved in mammary gland involution and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :0071353 and cellular response to interleukin-4 and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0090398 and cellular senescence and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :1902187 and negative regulation of viral release from host cell and biological process this GO :2000059 and negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :2000779 and regulation of double-strand break repair and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045947 and negative regulation of translational initiation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051018 and protein kinase A binding and molecular function this GO :0051099 and positive regulation of binding and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0055012 and ventricular cardiac muscle cell differentiation and biological process this GO :0060010 and Sertoli cell fate commitment and biological process this GO :0060173 and limb development and biological process this GO :0060324 and face development and biological process this GO :0060348 and bone development and biological process this GO :0060534 and trachea cartilage development and biological process this GO :0060591 and chondroblast differentiation and biological process this GO :0061037 and negative regulation of cartilage development and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071391 and cellular response to estrogen stimulus and biological process, MYL and PP8675 and RNF71 and TRIM19, NR1B1 and RAR, PML and IDBG-21462 and ENSG00000140464 and 5371, PML and IDBG-631902 and ENSBTAG00000015779 and 100138545, PML-RARA regulated adaptor molecule 1, PRAM1 and IDBG-24943 and ENSG00000133246 and 84106, PRAM1 and IDBG-643837 and ENSBTAG00000021041 and 504848, Pml and IDBG-171712 and ENSMUSG00000036986 and 18854, Pram1 and IDBG-167526 and ENSMUSG00000032739 and 378460, RARA and IDBG-47411 and ENSG00000131759 and 5914, RARA and IDBG-639652 and ENSBTAG00000012500 and 534280, Rara and IDBG-210842 and ENSMUSG00000037992 and 19401, alpha, cobalt ion binding, lipid binding, multiple, nuclei, nuclei, nucleic acid binding, nucleic acid binding and also this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001012: RNA polymerase II regulatory region DNA binding and also this GO :0001972: retinoic acid binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003707: steroid hormone receptor activity and also this GO :0003708: retinoic acid receptor activity and also this GO :0003713: transcription coactivator activity and also this GO :0003714: transcription corepressor activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0008144: drug binding and also this GO :0008270: zinc ion binding and also this GO :0019899: enzyme binding and also this GO :0019904: protein domain specific binding and also this GO :0031490: chromatin DNA binding and also this GO :0035014: phosphatidylinositol 3-kinase regulator activity and also this GO :0043422: protein kinase B binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0044323: retinoic acid-responsive element binding and also this GO :0046982: protein heterodimerization activity and also this GO :0048027: mRNA 5'-UTR binding and also this GO :0051018: protein kinase A binding, nucleic acid binding and molecular function this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001012 and RNA polymerase II regulatory region DNA binding and molecular function this GO :0001657 and ureteric bud development and biological process this GO :0001843 and neural tube closure and biological process this GO :0001889 and liver development and biological process this GO :0001972 and retinoic acid binding and molecular function this GO :0002068 and glandular epithelial cell development and biological process this GO :0003148 and outflow tract septum morphogenesis and biological process this GO :0003417 and growth plate cartilage development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0003708 and retinoic acid receptor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, retinoic acid receptor, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007182 and common-partner SMAD protein phosphorylation and biological process this GO :0007184 and SMAD protein import into nucleus and biological process this GO :0007569 and cell aging and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0009411 and response to UV and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0010522 and regulation of calcium ion transport into cytosol and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0016605 and PML body and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030578 and PML body organization and biological process this GO :0031065 and positive regulation of histone deacetylation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031901 and early endosome membrane and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032183 and SUMO binding and molecular function this GO :0032211 and negative regulation of telomere maintenance via telomerase and biological process this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0032938 and negative regulation of translation in response to oxidative stress and biological process this GO :0034097 and response to cytokine and biological process this GO :0042406 and extrinsic component of endoplasmic reticulum membrane and cellular component this GO :0042752 and regulation of circadian rhythm and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043153 and entrainment of circadian clock by photoperiod and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045343 and regulation of MHC class I biosynthetic process and biological process this GO :0045892 and negative regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000900 and translation repressor activity, this GO :0000900: translation repressor activity, this GO :0000900: translation repressor activity, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0001012: RNA polymerase II regulatory region DNA binding, this GO :0001666 and response to hypoxia and biological process this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0003677 and DNA binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0001972: retinoic acid binding, this GO :0003677: DNA binding, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0032183: SUMO binding and also this GO :0042803: protein homodimerization activity and also this GO :0046332: SMAD binding and also this GO :0046982: protein heterodimerization activity and also this GO :0050897: cobalt ion binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003707: steroid hormone receptor activity, this GO :0003708: retinoic acid receptor activity, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity, this GO :0003714: transcription corepressor activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005102: receptor binding, this GO :0005515 and protein binding and molecular function this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008289 and lipid binding and molecular function this GO :0043313 and regulation of neutrophil degranulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008289: lipid binding, this GO :0008134: transcription factor binding, this GO :0008144: drug binding, this GO :0008270: zinc ion binding, this GO :0008270: zinc ion binding, this GO :0008289: lipid binding, this GO :0019899: enzyme binding, this GO :0019904: protein domain specific binding, this GO :0031490: chromatin DNA binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0032183: SUMO binding, this GO :0035014: phosphatidylinositol 3-kinase regulator activity, this GO :0042803: protein homodimerization activity, this GO :0043422: protein kinase B binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0044323: retinoic acid-responsive element binding, this GO :0046332: SMAD binding, this GO :0046982: protein heterodimerization activity, this GO :0046982: protein heterodimerization activity, this GO :0048027: mRNA 5'-UTR binding, this GO :0050897: cobalt ion binding, this GO :0051018: protein kinase A binding, translation repressor activity, promyelocytic leukemia |
| Identity | 30091 |
| Gene | PRAM1 |
| Long gene name | PML-RARA regulated adaptor molecule 1 |
| Synonyms | PML-RAR |
| Locus | 19p13, 2 |
| Discovery year | 2005-07-04 |
| GenBank acession | BC028012 |
| Entrez gene record | 84106 |
| Pubmed identfication | 11301322 15572693 |
| RefSeq identity | NM_032152 |
| Havana BLAST/BLAT | OTTHUMG00000167924 |