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PRAME Antibody

PRAME Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePRAME Primary Polyclonal Antibody
Also known asPRAME PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPRAME
SpecificityThis is a highly specific antibody against PRAME
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range180-227/509
Subcellular location Cell membrane, Nucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRAME
Gene ID number23532
Swiss ProtP78395
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Prevents retinoic acid-induced cell proliferation arrest, RARB and RARG, differentiation and apoptosis, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, Functions as a transcriptional repressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CT130, Melanoma antigen preferentially expressed in tumors, OIP-4, OIP4, Opa-interacting protein 4, PRAME, Preferentially expressed antigen of melanoma, MAPE
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPRAME
Short namePRAME Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namepreferentially expressed antigen in melanoma (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CT130 and MAPE and OIP-4 and OIP4, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030154 and cell differentiation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042974 and retinoic acid receptor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process, PRAME and IDBG-2240 and ENSG00000185686 and 23532, nuclei, retinoic acid receptor binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0042974: retinoic acid receptor binding, this GO :0042974: retinoic acid receptor binding, preferentially expressed antigen in melanoma
Identity 9336
Gene PRAME
Long gene name preferentially expressed antigen in melanoma
Synonyms gene MAPE
Synonyms CT130
Synonyms name cancer/testis antigen 130
Locus 22q11, 22
Discovery year 1996-06-21
GenBank acession U65011
Entrez gene record 23532
Pubmed identfication 9047241 10591208
RefSeq identity NM_206953
Classification PRAME family
Havana BLAST/BLAT OTTHUMG00000151172

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