Name : PRAME Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2655235945
| Long name | Cy3 Conjugated, PRAME Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PRAME |
| Specificity | This is a highly specific antibody against PRAME |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 180-227/509 |
| Subcellular location | Cell membrane, Nucleus |
| Source | KLH conjugated synthetic peptide derived from human PRAME |
| Gene ID number | 23532 |
| Swiss Prot | P78395 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Prevents retinoic acid-induced cell proliferation arrest, RARB and RARG, differentiation and apoptosis, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, Functions as a transcriptional repressor |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | CT130 |
| Properties | 1 of the PRAME Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRAME Conjugated |
| Short name | Conjugated, PRAME Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, preferentially expressed antigen in melanoma (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CT130 and MAPE and OIP-4 and OIP4, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030154 and cell differentiation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042974 and retinoic acid receptor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process, PRAME and IDBG-2240 and ENSG00000185686 and 23532, nuclei, retinoic acid receptor binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0042974: retinoic acid receptor binding, this GO :0042974: retinoic acid receptor binding, preferentially expressed antigen in melanoma |
| Identity | 9336 |
| Gene | PRAME |
| Long gene name | preferentially expressed antigen in melanoma |
| Synonyms gene | MAPE |
| Synonyms name | cancer/testis antigen 130 |
| Locus | 22q11, 22 |
| Discovery year | 1996-06-21 |
| GenBank acession | U65011 |
| Entrez gene record | 23532 |
| Pubmed identfication | 9047241 10591208 |
| RefSeq identity | NM_206953 |
| Classification | PRAME family |
| Havana BLAST/BLAT | OTTHUMG00000151172 |