| Long name | PRDX1 Primary Polyclonal Antibody |
| Also known as | PRDX1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PRDX1 |
| Specificity | This is a highly specific antibody against PRDX1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 63-88/199 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRDX1 |
| Gene ID number | 5052 |
| Swiss Prot | Q06830 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | May play an important role in eliminating peroxides generated during metabolism, Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2), Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity), Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin, Involved in redox regulation of the cell |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MSP23, NKEF-A, NKEFA, Natural killer cell-enhancing factor A, PAGA, PAGB, PRDX1, PRX1, PRXI, Peroxiredoxin-1, Proliferation-associated gene protein, TDPX2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, PAG |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRDX1 |
| Short name | PRDX1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | peroxiredoxin 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MSP23 and NKEF-A and NKEFA and PAG and PAGA and PAGB and PRX1 and PRXI and TDPX2, PRDX1 and IDBG-640075 and ENSBTAG00000003642 and 281997, PRDX1 and IDBG-97953 and ENSG00000117450 and 5052, Prdx1 and IDBG-178542 and ENSMUSG00000028691 and 18477, nuclei, peroxiredoxin activity, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001501 and skeletal system development and biological process this GO :0001895 and retina homeostasis and biological process this GO :0004601 and peroxidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005719 and nuclear euchromatin and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0006979 and response to oxidative stress and biological process this GO :0008283 and cell proliferation and biological process this GO :0008379 and thioredoxin peroxidase activity and molecular function this GO :0016209 and antioxidant activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0020037 and heme binding and molecular function this GO :0032872 and regulation of stress-activated MAPK cascade and biological process this GO :0034101 and erythrocyte homeostasis and biological process this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0042345 and regulation of NF-kappaB import into nucleus and biological process this GO :0042470 and melanosome and cellular component this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051920 and peroxiredoxin activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004601: peroxidase activity, this GO :0004601: peroxidase activity and also this GO :0005515: protein binding and also this GO :0008379: thioredoxin peroxidase activity and also this GO :0016209: antioxidant activity and also this GO :0016491: oxidoreductase activity and also this GO :0020037: heme binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0044822: poly(A) RNA binding and also this GO :0051920: peroxiredoxin activity, this GO :0005515: protein binding, this GO :0008379: thioredoxin peroxidase activity, this GO :0016209: antioxidant activity, this GO :0016491: oxidoreductase activity, this GO :0020037: heme binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0044822: poly(A) RNA binding, this GO :0051920: peroxiredoxin activity, peroxiredoxin 1 |
| Identity | 9352 |
| Gene | PRDX1 |
| Long gene name | peroxiredoxin 1 |
| Synonyms gene | PAGA |
| Synonyms | NKEFA |
| Locus | 1p34, 1 |
| Discovery year | 1993-11-01 |
| GenBank acession | BC021683 |
| Entrez gene record | 5052 |
| Pubmed identfication | 8496166 |
| RefSeq identity | NM_181697 |
| Classification | Peroxiredoxins |
| Havana BLAST/BLAT | OTTHUMG00000007738 |
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