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Presenilin 1 + 2 Antibody, Biotin Conjugated

Presenilin 1 + 2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Presenilin 1 + 2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPresenilin 1 + 2
SpecificityThis is a highly specific antibody against Presenilin 1 + 2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Presenilin-1/ Presenilin-2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background PSEN2) or the amyloid precursor protein (APP), Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains), an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP, Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AD4, AD5, Alzheimer disease 3, Alzheimer disease 4, FAD, PS-1, PS-2, PS1, PS2, PSEN1, PSEN2, PSN1_HUMAN, PSN2_HUMAN, Presenilin 1, Presenilin 2, Presenilin-1, Presenilin-2, Presenilin1, Presenilin1, STM2, AD 3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPresenilin 1 + 2 Conjugated
Short name Conjugated, Presenilin 1 + 2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Presenilin 1 and 2 (Antibody to)
Alternative techniqueantibodies

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