| Long name | presenilin 1 Primary Polyclonal Antibody |
| Also known as | presenilin 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | presenilin 1 |
| Specificity | This is a highly specific antibody against presenilin 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/467 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from rat presenilin 1 |
| Gene ID number | 29192 |
| Swiss Prot | P97887 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rabbit, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | May also play a role in hematopoiesis (By similarity), May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane, Requires the other members of the gamma-secretase complex to have a protease activity, Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex, Under conditions of apoptosis or calcium influx, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling, Probable catalytic subunit of the gamma-secretase complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | PS-1, Protein S182, Psen1, Psnl1, Presenilin-1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | presenilin 1 |
| Short name | presenilin 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | presenilin 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18253 |
| Gene | PARL |
| Long gene name | presenilin associated rhomboid like |
| Synonyms gene | PSARL |
| Synonyms gene name | presenilin associated, rhomboid-like |
| Synonyms | PRO2207 PSARL1 RHBDS1 |
| Synonyms name | rhomboid 7 homolog 1 (Drosophila) |
| Locus | 3q27, 1 |
| Discovery year | 2003-09-03 |
| GenBank acession | AF116692 |
| Entrez gene record | 55486 |
| RefSeq identity | NM_018622 |
| Classification | Rhomboid family |
| Havana BLAST/BLAT | OTTHUMG00000156890 |
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