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Prion protein PrP/CD230 Antibody, FITC Conjugated

Prion protein PrP/CD230 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, Prion protein PrP/CD230 Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPrion protein PrP/CD230
SpecificityThis is a highly specific antibody against Prion protein PrP/CD230
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Prion protein PrP/CD230
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase, May be required for neuronal myelin sheath maintenance, May play a role in iron uptake and iron homeostasis (By similarity), May play a role in neuronal development and synaptic plasticity, Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro), The function of PrP is still under debate
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CD230 PRP AltPrP
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPrion protein PrP/CD230 Conjugated
Short name FITC Conjugated, Prion protein PrP/CD230 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Prion protein PrP/CD230 (Antibody to)
Alternative techniqueantibodies
Identity 9449
Gene PRNP
Long gene name prion protein
Synonyms gene PRIP GSS CJD
Synonyms gene name prion protein (p27-30)
Synonyms name Creutzfeldt-Jakob disease Gerstmann-Strausler-Scheinker syndrome fatal familial insomnia p27-30
Locus 20p13
Discovery year 1986-01-01
GenBank acession M13899
Entrez gene record 5621
RefSeq identity NM_000311
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000031786
Locus Specific Databases Prion Protein/CJD database

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