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PRK1 (Thr774)/PRK2 (Thr816) Antibody

PRK1 (Thr774)/PRK2 (Thr816) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePRK1 (Thr774)/PRK2 (Thr816) Antibody
Also known asPRK1 (Thr774)/PRK2 (Thr816) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPRK1 Thr774 + PRK2 Thr816
SpecificityThis is a highly specific antibody against PRK1 Thr774 + PRK2 Thr816
Modification(s)Phosphorylation
Modification site(s)Thr816
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774
Gene ID number5585
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen EG-VEGF, EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner, EG-VEGF possesses an HIF-1 binding site, Expression of EG-VEGF is often complementary to the expression of VEGF, It is expressed primarily in one type of tissue and acts selectively on one type of endothelium, adrenal and placenta), and fenestration in capillary endothelial cells derived from endocrine glands, its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, leading to proliferation, migration, migration and survival of responsive endothelial cells , possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, suggesting that these molecules function in a coordinated manner, testis, Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EG-VEGF, EGVEGF, PK1, PRK1, PROK1, Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPRK1 (Thr774)/PRK2 (Thr816)
Short namePRK1 (Thr774)/PRK2 (Thr816) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePRK1 (Thr774)/PRK2 (Thr816) (Antibody to)
Alternative techniqueantibodies
Identity 9406
Gene PKN2
Long gene name protein kinase N2
Synonyms gene PRKCL2
Synonyms gene name protein kinase C-like 2
Synonyms PRK2 Pak-2 STK7
Synonyms name cardiolipin-activated protein kinase Pak2
Locus 1p22, 2
Discovery year 1997-10-10
GenBank acession U33052
Entrez gene record 5586
Pubmed identfication 7988719 7851406
RefSeq identity NM_006256
Classification C2 domain containing protein kinases
Havana BLAST/BLAT OTTHUMG00000010074

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