Name : PRK1 (Thr774)/PRK2 (Thr816) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN4739718513
| Long name | ALEXA FLUOR 488 Conjugated, PRK1 (Thr774)/PRK2 (Thr816) Antibody |
| Also known as | Anti-PRK1 Thr774 + PRK2 Thr816 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PRK1 Thr774 + PRK2 Thr816 |
| Specificity | This is a highly specific antibody against PRK1 Thr774 + PRK2 Thr816 |
| Modification | Phosphorylation |
| Modification Site | Thr816 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774 |
| Gene ID Number | 5585 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | EG-VEGF, EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner, EG-VEGF possesses an HIF-1 binding site, Expression of EG-VEGF is often complementary to the expression of VEGF, It is expressed primarily in one type of tissue and acts selectively on one type of endothelium, adrenal and placenta), and fenestration in capillary endothelial cells derived from endocrine glands, its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, leading to proliferation, migration, migration and survival of responsive endothelial cells , possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, suggesting that these molecules function in a coordinated manner, testis, Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | PRK2 Pak-2 STK7 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PRK1 (Thr774)/PRK2 (Thr816) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | PRK1 (Thr774)/PRK2 (Thr816) |
| Short name | PRK1 (Thr774)/PRK2 (Thr816) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, PRK1 (Thr774)/PRK2 (Thr816) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9406 |
| Gene | PKN2 |
| Long gene name | protein kinase N2 |
| Synonyms gene | PRKCL2 |
| Synonyms gene name | protein kinase C-like 2 |
| Synonyms name | cardiolipin-activated protein kinase Pak2 |
| Locus | 1p22, 2 |
| Discovery year | 1997-10-10 |
| GenBank acession | U33052 |
| Entrez gene record | 5586 |
| Pubmed identfication | 7988719 7851406 |
| RefSeq identity | NM_006256 |
| Classification | C2 domain containing protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000010074 |