Name : PRK1 (Thr774)/PRK2 (Thr816) Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7379131998
| Long name | FITC Conjugated, PRK1 (Thr774)/PRK2 (Thr816) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PRK1 Thr774 + PRK2 Thr816 |
| Specificity | This is a highly specific antibody against PRK1 Thr774 + PRK2 Thr816 |
| Modification | Phosphorylation |
| Modification site | Thr816 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774 |
| Gene ID number | 5585 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | EG-VEGF, EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner, EG-VEGF possesses an HIF-1 binding site, Expression of EG-VEGF is often complementary to the expression of VEGF, It is expressed primarily in one type of tissue and acts selectively on one type of endothelium, adrenal and placenta), and fenestration in capillary endothelial cells derived from endocrine glands, its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, leading to proliferation, migration, migration and survival of responsive endothelial cells , possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, suggesting that these molecules function in a coordinated manner, testis, Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | PRK2 Pak-2 STK7 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRK1 (Thr774)/PRK2 (Thr816) Conjugated |
| Short name | FITC Conjugated, PRK1 (Thr774)/PRK2 (Thr816) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PRK1 (Thr774)/PRK2 (Thr816) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9406 |
| Gene | PKN2 |
| Long gene name | protein kinase N2 |
| Synonyms gene | PRKCL2 |
| Synonyms gene name | protein kinase C-like 2 |
| Synonyms name | cardiolipin-activated protein kinase Pak2 |
| Locus | 1p22, 2 |
| Discovery year | 1997-10-10 |
| GenBank acession | U33052 |
| Entrez gene record | 5586 |
| Pubmed identfication | 7988719 7851406 |
| RefSeq identity | NM_006256 |
| Classification | C2 domain containing protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000010074 |