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PRKAR1 Antibody, ALEXA FLUOR 350

PRKAR1 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, PRKAR1 Polyclonal Antibody
Also known asAnti-PRKAR1 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPRKAR1
SpecificityThis is a highly specific antibody against PRKAR1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Protein Kinase A regulatory subunit I alpha
Gene ID Number5573
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40), Four different regulatory subunits and three catalytic subunits have been identified in humans, Jul 2008], Mutations in this gene cause Carney complex (CNC), The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits, This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2, This gene encodes one of the regulatory subunits, This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids, Three alternatively spliced transcript variants encoding the same protein have been observed, [provided by RefSeq, cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits, cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins, cAMP is a signaling molecule important for a variety of cellular functions
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms CNC1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetPRKAR1
Short namePRKAR1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, PRKAR1 (Antibody to)
Alternative techniqueantibodies
Identity 9388
Gene PRKAR1A
Long gene name protein kinase cAMP-dependent type I regulatory subunit alpha
Synonyms gene PRKAR1 TSE1
Synonyms gene name alpha protein kinase, cAMP-dependent, cAMP-dependent, regulatory, regulatory subunit type I alpha , tissue specific extinguisher 1 protein kinase, type I
Synonyms name Carney complex type 1
Locus 17q24, 2
Discovery year 1988-05-11
Entrez gene record 5573
Pubmed identfication 3479018 10973256
Havana BLAST/BLAT OTTHUMG00000180128
Locus Specific Databases LRG_514

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