| Long name | PRKCB(Ser660) Primary Polyclonal Antibody |
| Also known as | PRKCB(Ser660) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PRKCB Ser660 |
| Specificity | This is a highly specific antibody against PRKCB Ser660 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser660 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PRKCZ around the phosphorylation site of Ser660 |
| Gene ID number | 5590 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alternatively spliced transcript variants encoding distinct isoforms have been reported, Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells, PKC family members also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress, The protein encoded by this gene is one of the PKC family members, This protein kinase has been reported to be involved in many different cellular functions, a class of tumor promoters, and intestinal sugar absorption, apoptosis induction, endothelial cell proliferation, such as B cell activation, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AAG6, Aging associated gene 6, MGC129900, MGC129901, MGC41878, MGC57564, PKC B, PKC beta, PKC zeta, PKC2, PKCB, PKCC, PKCD, PKCE, PKCG, PRKACA, PRKC A, PRKC G, PRKCA, PRKCB, PRKCB1, PRKCB2, PRKCD, PRKCE, PRKCG, PRKCZ , Protein Kinase C, Protein kinase C alpha, Protein kinase C alpha type, Protein kinase C beta, Protein kinase C beta 1, Protein kinase C beta 1 polypeptide, Protein kinase C beta type, Protein kinase C delta, Protein kinase C epsilon, Protein kinase C gamma, Protein kinase C gamma type, Protein kinase C zeta, SCA14, Spinocerebellar ataxia 14, rotein Kinase C, PRKCBphospho S660 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRKCB(Ser660) |
| Short name | PRKCB(Ser660) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | b(Ser660) (Antibody to), protein kinase C |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007596 and blood coagulation and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010829 and negative regulation of glucose transport and biological process this GO :0016772 and transferase activity, PKC-beta and PKCB and PRKCB1 and PRKCB2, PRKCB and IDBG-20895 and ENSG00000166501 and 5579, PRKCB and IDBG-638608 and ENSBTAG00000020921 and 282325, Prkcb and IDBG-208976 and ENSMUSG00000052889 and 18751, beta, nuclei, this GO :0003682 and chromatin binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004697 and protein kinase C activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004697: protein kinase C activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005080: protein kinase C binding and also this GO :0005246: calcium channel regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008270: zinc ion binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004697: protein kinase C activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005080: protein kinase C binding, this GO :0005246: calcium channel regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008270: zinc ion binding, this GO :0016772: transferase activity, this GO :0030374: ligand-dependent nuclear receptor transcription coactivator activity, this GO :0035403: histone kinase activity (H3-T6 specific), this GO :0042393: histone binding, this GO :0050681: androgen receptor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030374: ligand-dependent nuclear receptor transcription coactivator activity and also this GO :0035403: histone kinase activity (H3-T6 specific) and also this GO :0042393: histone binding and also this GO :0050681: androgen receptor binding, transferring phosphorus-containing groups and molecular function this GO :0030168 and platelet activation and biological process this GO :0030374 and ligand-dependent nuclear receptor transcription coactivator activity and molecular function this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0035403 and histone kinase activity (H3-T6 specific) and molecular function this GO :0035408 and histone H3-T6 phosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042113 and B cell activation and biological process this GO :0042393 and histone binding and molecular function this GO :0042953 and lipoprotein transport and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0050681 and androgen receptor binding and molecular function this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0050861 and positive regulation of B cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071322 and cellular response to carbohydrate stimulus and biological process, protein kinase C |
| Identity | 9395 |
| Gene | PRKCB |
| Long gene name | protein kinase C beta |
| Synonyms gene | PRKCB2 PKCB PRKCB1 |
| Synonyms gene name | beta , beta 1 protein kinase C, protein kinase C |
| Locus | 16p12, 1 , 2-p12 |
| Discovery year | 1991-08-02 |
| GenBank acession | M13975 |
| Entrez gene record | 5579 |
| Pubmed identfication | 3658678 |
| RefSeq identity | NM_212535 |
| Classification | C2 domain containing protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000131615 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue