| Long name | PRKCQ(Ser695) Primary Polyclonal Antibody |
| Also known as | PRKCQ(Ser695) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PRKCQ Ser695 |
| Specificity | This is a highly specific antibody against PRKCQ Ser695 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser695 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse PRKCQ around the phosphorylation site of Ser695 |
| Gene ID number | 18761 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Essential for T-cell receptor (TCR)-mediated T-cell activation, Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes, PKC also serves as the receptor for phorbol esters, PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins, Required for interleukin-2 (IL2) production, a class of tumor promoters, but is dispensable during TCR-dependent thymocyte development, phospholipid-dependent, serine- and threonine-specific enzyme, This is a calcium-independent |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | KPCT_HUMAN, PKC 0, PKC thetaphospho S695, PKCÎ, PKC0, PRKCQ, PRKCT, Prkcq, Protein Kinase Ctheta, Protein kinase C theta, Protein kinase C theta type, nPKC theta, nPKC-theta, nPKCtheta, ¸, PRKCQphospho S695, Ser695 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRKCQ(Ser695) |
| Short name | PRKCQ(Ser695) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | theta(Ser695) (Antibody to), protein kinase C |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0007603 and phototransduction, PRKCQ and IDBG-51302 and ENSG00000065675 and 5588, PRKCQ and IDBG-637023 and ENSBTAG00000010664 and 505901, Prkcq and IDBG-136196 and ENSMUSG00000026778 and 18761, nPKC-theta and PRKCT, theta, this GO :0001558 and regulation of cell growth and biological process this GO :0001772 and immunological synapse and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004697 and protein kinase C activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004697: protein kinase C activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004697: protein kinase C activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004842: ubiquitin-protein transferase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0022400 and regulation of rhodopsin mediated signaling pathway and biological process this GO :0030168 and platelet activation and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070233 and negative regulation of T cell apoptotic process and biological process this GO :0090330 and regulation of platelet aggregation and biological process this GO :2000318 and positive regulation of T-helper 17 type immune response and biological process this GO :2000570 and positive regulation of T-helper 2 cell activation and biological process, visible light and biological process this GO :0016056 and rhodopsin mediated signaling pathway and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016772 and transferase activity, protein kinase C |
| Identity | 9410 |
| Gene | PRKCQ |
| Long gene name | protein kinase C theta |
| Synonyms gene name | protein kinase C, theta |
| Locus | 10p15, 1 |
| Discovery year | 1992-12-14 |
| GenBank acession | L07032 |
| Entrez gene record | 5588 |
| Pubmed identfication | 8444877 |
| RefSeq identity | NM_006257 |
| Classification | C2 domain containing protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000017623 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue