Name : PRMT5 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9506376094
| Long name | Cy3 Conjugated, PRMT5 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PRMT5 |
| Specificity | This is a highly specific antibody against PRMT5 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PRMT5 |
| Gene ID number | 10419 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | May be part of a pathway that is connected to a chloride current, May play a role in cytokine-activated transduction pathways, May regulate the SUPT5H transcriptional elongation properties, Methylates RPS10, Methylates SUPT5H, Methylates histone H2A and H4 'Arg-3' during germ cell development, Methylates histone H3 'Arg-8', Methylates the Piwi proteins (PIWIL1, Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro, Negatively regulates cyclin E1 promoter activity and cellular proliferation, PIWIL2 and PIWIL4), Plays a role in the assembly of snRNP core particles, Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage, possibly through cytoskeletal rearrangement, such methylation being required for the assembly and biogenesis of snRNP core particles, which may repress transcription, with a preference for the formation of MMA, Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | SKB1Hs |
| Properties | 1 of the PRMT5 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRMT5 Conjugated |
| Short name | Conjugated, PRMT5 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, PRMT5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10894 |
| Gene | PRMT5 |
| Long gene name | protein arginine methyltransferase 5 |
| Synonyms gene | HRMT1L5 SKB1 |
| Synonyms gene name | pombe) , pombe) homolog SKB1 homolog (S, skb1 (S |
| Locus | 14q11, 2 |
| Discovery year | 1999-06-18 |
| GenBank acession | AF015913 |
| Entrez gene record | 10419 |
| Pubmed identfication | 9843966 |
| Classification | Protein arginine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000028709 |